Monday, November 29, 2021

                                                                                       

Hair loss

 



 

Overview

Hair loss (alopecia) can affect just your scalp or your entire body, and it can be temporary or permanent. It can be the result of heredity, hormonal changes, medical conditions or a normal part of aging. Anyone can lose hair on their head, but it's more common in men.

 

Baldness typically refers to excessive hair loss from your scalp. Hereditary hair loss with age is the most common cause of baldness. Some people prefer to let their hair loss run its course untreated and unhidden. Others may cover it up with hairstyles, makeup, hats or scarves. And still others choose one of the treatments available to prevent further hair loss or restore growth.

 

Before pursuing hair loss treatment, talk with your doctor about the cause of your hair loss and treatment options.

Symptoms                                                                    


 

Hair loss can appear in many different ways, depending on what's causing it.

In men, hair often begins to recede from the forehead.

Women tend to lose hair along the part.

Patchy hair loss (alopecia areata) is sometimes preceded by itchy or painful scalp.

Repeated stress on the hair can cause a type of hair loss called traction alopecia.

 

Signs and symptoms of hair loss may include:

 

Gradual thinning on top of head. This is the most common type of hair loss, affecting people as they age. In men, hair often begins to recede at the hairline on the forehead. Women typically have a broadening of the part in their hair. An increasingly common hair loss pattern in older women is a receding hairline (frontal fibrosing alopecia).

Circular or patchy bald spots. Some people lose hair in circular or patchy bald spots on the scalp, beard or eyebrows. Your skin may become itchy or painful before the hair falls out.

Sudden loosening of hair. A physical or emotional shock can cause hair to loosen. Handfuls of hair may come out when combing or washing your hair or even after gentle tugging. This type of hair loss usually causes overall hair thinning but is temporary.

Full-body hair loss. Some conditions and medical treatments, such as chemotherapy for cancer, can result in the loss of hair all over your body. The hair usually grows back.

Patches of scaling that spread over the scalp. This is a sign of ringworm. It may be accompanied by broken hair, redness, swelling and, at times, oozing.

When to see a doctor

See your doctor if you are distressed by persistent hair loss in you or your child and want to pursue treatment. For women who are experiencing a receding hairline (frontal fibrosing alopecia), talk with your doctor about early treatment to avoid significant permanent baldness.

 

Also talk to your doctor if you notice sudden or patchy hair loss or more than usual hair loss when combing or washing your or your child's hair. Sudden hair loss can signal an underlying medical condition that requires treatment.

 

Causes

People typically lose 50 to 100 hairs a day. This usually isn't noticeable because new hair is growing in at the same time. Hair loss occurs when new hair doesn't replace the hair that has fallen out.

 

Hair loss is typically related to one or more of the following factors:

 

Family history (heredity). The most common cause of hair loss is a hereditary condition that happens with aging. This condition is called androgenic alopecia, male-pattern baldness and female-pattern baldness. It usually occurs gradually and in predictable patterns — a receding hairline and bald spots in men and thinning hair along the crown of the scalp in women.

Hormonal changes and medical conditions. A variety of conditions can cause permanent or temporary hair loss, including hormonal changes due to pregnancy, childbirth, menopause and thyroid problems. Medical conditions include alopecia areata which is immune system related and causes patchy hair loss, scalp infections such as ringworm, and a hair-pulling disorder called trichotillomania.

Medications and supplements. Hair loss can be a side effect of certain drugs, such as those used for cancer, arthritis, depression, heart problems, gout and high blood pressure.

Radiation therapy to the head. The hair may not grow back the same as it was before.

A very stressful event. Many people experience a general thinning of hair several months after a physical or emotional shock. This type of hair loss is temporary.

Hairstyles and treatments. Excessive hairstyling or hairstyles that pull your hair tight, such as pigtails or cornrows, can cause a type of hair loss called traction alopecia. Hot-oil hair treatments and permanents also can cause hair to fall out. If scarring occurs, hair loss could be permanent.

 

Frontal fibrosing alopecia

Risk factors

A number of factors can increase your risk of hair loss, including:

 

A family history of balding on your mother's or father's side

Age

Significant weight loss

Certain medical conditions, such as diabetes and lupus

Stress

Poor nutrition

Prevention

Most baldness is caused by genetics (male-pattern baldness and female-pattern baldness). This type of hair loss is not preventable.

 

These tips may help you avoid preventable types of hair loss:

 

Be gentle with your hair. Use a detangler and avoid tugging when brushing and combing, especially when your hair is wet. A wide-toothed comb might help prevent pulling out hair. Avoid harsh treatments such as hot rollers, curling irons, hot-oil treatments and permanents. Limit the tension on hair from styles that use rubber bands, barrettes and braids.

Ask your doctor about medications and supplements you take that might cause hair loss.

Protect your hair from sunlight and other sources of ultraviolet light.

Stop smoking. Some studies show an association between smoking and baldness in men.

If you're being treated with chemotherapy, ask your doctor about a cooling cap. This cap can reduce your risk of losing hair during chemotherapy.


 

 


 

Jan Ricks Jennings, MHA, LFACHE

Senior Consultant

Senior Management Resources, LLC

 

Jan.Jennings@EagleTalons.net

JanJennings@EagleTalons.net

 

412.913.0636 Cell

724.733.0509 Office

November 27, 2019

 

Thursday, November 25, 2021

                                                                                  

Elevated blood pressure


 



Elevated blood pressure means that your blood pressure is slightly above what is considered normal. Some doctors refer to slightly elevated blood pressure as prehypertension. Elevated blood pressure will likely turn into high blood pressure (hypertension) unless you make lgetting more and eating healthier foods.

 

Anyone can have elevated blood pressure, even children, especially if they're overweight or obese.

 

Both elevated blood pressure and high blood pressure increase your risk of a heart attack, stroke and heart failure. Some research suggests that long-term (chronic) elevated blood pressure may contribute to cognitive decline. Weight loss, exercise and other healthy lifestyle changes can often control elevated blood pressure and set the stage for a lifetime of better health.

 

Symptoms

Elevated blood pressure doesn't cause symptoms. The only way to detect it is to keep track of your blood pressure readings. Have your blood pressure checked at each doctor's visit — or check it at home with a home blood pressure monitoring device.  Some pharmacies also have blood pressure machines.                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                   When to see a doctor                                                                                                                                                                                                                                                      All people age 3 and older should have their blood pressure checked by a doctor at least once a year. You might need more frequent readings if you have elevated blood pressure or other risk factors for cardiovascular disease.

 

Causes

Any factor that increases pressure against the artery walls can lead to elevated blood pressure. The buildup of fatty deposits in your arteries (atherosclerosis) can lead to high blood pressure.

 

Besides atherosclerosis, other conditions that can lead to elevated blood pressure or high blood pressure include:

 

Obstructive sleep apnea                                            

Kidney disease

Adrenal disease

Thyroid disease   

 

 



                             

Certain medications — including birth control pills, cold remedies, decongestants, over-the-counter pain relievers and some prescription drugs — also can cause blood pressure to rise temporarily. Illegal drugs, such as cocaine and amphetamines, can have the same effect.

 

Risk factors

Risk factors for elevated blood pressure include:

 

Being overweight or obese. The greater your body mass, the more blood you need to supply oxygen and nutrients to your tissues. As the amount of blood going through your blood vessels increases, so does the force on your artery walls.

Sex. Elevated blood pressure is more common in men than in women through about age 55. Women are more likely to develop high blood pressure after age 55.

Race. Elevated blood pressure is particularly common among people of African heritage, often developing at an earlier age than it does in white people.

Family history of high blood pressure. If a first-degree relative, such as a parent or sibling, has high blood pressure, you're more likely to develop elevated blood pressure.

Not being physically active. Not exercising can cause weight gain and increase your risk of elevated blood pressure.

Diet high in salt (sodium) or low in potassium. Sodium and potassium are two key nutrients in the way your body regulates your blood pressure. If you have too much sodium or too little potassium in your diet, you're more likely to have elevated blood pressure.

Tobacco use. Smoking cigarettes, chewing tobacco or being around others who smoke (secondhand smoke) can increase your blood pressure.

Drinking too much alcohol. Alcohol use has been associated with elevated blood pressure, particularly in men.

Certain chronic conditions. Kidney disease, diabetes and sleep apnea, among others, can increase the risk of elevated blood pressure.

Although elevated blood pressure and high blood pressure are most common in adults, children can be at risk, too. For some children, kidney or heart problems can cause high blood pressure. But for a growing number of kids, poor lifestyle habits, such as an unhealthy diet, obesity and lack of exercise, contribute to elevated blood pressure and high blood pressure.

 

Complications

Elevated blood pressure is likely to worsen and develop into high blood pressure (hypertension). Hypertension can damage your organs and increase the risk of several conditions including a heart attack, heart failure, stroke, aneurysms and kidney failure.

 

Prevention

The same healthy lifestyle changes recommended to treat elevated blood pressure also help prevent hypertension. You've heard it before — eat healthy foods, use less salt, exercise regularly, maintain a healthy weight, drink less alcohol, manage stress and quit smoking. But take the advice to heart. Start adopting healthier habits today.

 

Jan Ricks Jennings, MHA, LFACHE

Senior Management Consultant

Senior Management Resources, LLC

 

Jan.Jennings@EagleTalons.net

JanJenningsBlog.Blogspot.com

 

412.913.0636 Cell

724.733.0509 Office

November 25, 2021

Wednesday, November 24, 2021

                                                                              

Pancreatic Cancer

 



 

Overview

 

Pancreatic cancer begins in the tissues of your pancreas — an organ in your abdomen that lies behind the lower part of your stomach. Your pancreas releases enzymes that aid digestion and produces hormones that help manage your blood sugar.

 

Several types of growths can occur in the pancreas, including cancerous and noncancerous tumors. The most common type of cancer that forms in the pancreas begins in the cells that line the ducts that carry digestive enzymes out of the pancreas (pancreatic ductal adenocarcinoma).

 

Pancreatic cancer is seldom detected at its early stages when it's most curable. This is because it often doesn't cause symptoms until after it has spread to other organs.

 

Pancreatic cancer treatment options are chosen based on the extent of the cancer. Options may include surgery, chemotherapy, radiation therapy or a combination of these

 

Symptoms                                                     


 

 

 

Signs and symptoms of pancreatic cancer often don't occur until the disease is advanced. They may include:

 

Abdominal pain that radiates to your back

Loss of appetite or unintended weight loss

Yellowing of your skin and the whites of your eyes (jaundice)

Light-colored stools

Dark-colored urine

Itchy skin

New diagnosis of diabetes or existing diabetes that's becoming more difficult to control

Blood clots

Fatigue

 

When to see a doctor

See your doctor if you experience any unexplained symptoms that worry you. Many other conditions can cause these symptoms, so your doctor may check for these conditions as well as for pancreatic cancer.         

                                                                     


 

  

                                                                                                                                                                 Jan Ricks Jennings, MHA, LFACHE

Senior Consultant

Senior Management Resources, LLC

Jan.Jennings@EagleTalons.net

JanJenningsBlog.Blogspot.com

724.733.0509 Office

412.913.0636 Cell

 

November 24, 2021

Tuesday, November 23, 2021

                                                                                       Acromegaly

                   

                                

 

 

Acromegaly is a hormonal disorder that develops when your pituitary gland produces too much growth hormone during adulthood.

 

When you have too much growth hormone, your bones increase in size. In childhood, this leads to increased height and is called gigantism. But in adulthood, a change in height doesn't occur. Instead, the increase in bone size is limited to the bones of your hands, feet and face, and is called acromegaly.

 

Because acromegaly is uncommon and the physical changes occur slowly over many years, the condition sometimes takes a long time to recognize. Untreated, high levels of growth hormone can affect other parts of the body, in addition to your bones. This can lead to serious — sometimes even life-threatening — health problems. But treatment can reduce your risk of complications and significantly improve your symptoms, including the enlargement of your features.

Symptoms

A common sign of acromegaly is enlarged hands and feet. For example, you may notice that you aren't able to put on rings that used to fit, and that your shoe size has progressively increased.

 

Acromegaly may also cause gradual changes in your face's shape, such as a protruding lower jaw and brow bone, an enlarged nose, thickened lips, and wider spacing between your teeth.

 

Because acromegaly tends to progress slowly, early signs may not be obvious for years. Sometimes, people notice the physical changes only by comparing old photos with newer ones.

 

Overall, acromegaly signs and symptoms tend to vary from one person to another, and may include any of the following:

 

Enlarged hands and feet

Enlarged facial features, including the facial bones, lips, nose and tongue

Coarse, oily, thickened skin

Excessive sweating and body odor

Small outgrowths of skin tissue (skin tags)

Fatigue and joint or muscle weakness

Pain and limited joint mobility

A deepened, husky voice due to enlarged vocal cords and sinuses

Severe snoring due to obstruction of the upper airway

Vision problems

Headaches, which may be persistent or severe

Menstrual cycle irregularities in women

Erectile dysfunction in men

Loss of interest in sex

When to see a doctor

If you have signs and symptoms associated with acromegaly, contact your doctor for an exam.

 

Acromegaly usually develops slowly. Even your family members may not notice the gradual physical changes that occur with this disorder at first. But early diagnosis is important so that you can start getting proper care. Acromegaly can lead to serious health problems if it's not treated.

 

Causes

Pituitary gland and hypothalamus

Pituitary gland and hypothalamu

Acromegaly occurs when the pituitary gland produces too much growth hormone (GH) over a long period of time.

 

The pituitary gland is a small gland at the base of your brain, behind the bridge of your nose. It produces GH and a number of other hormones. GH plays an important role in managing your physical growth.

 

When the pituitary gland releases GH into your bloodstream, it triggers your liver to produce a hormone called insulin-like growth factor-1 (IGF-1) — sometimes also called insulin-like growth factor-I, or IGF-I. IGF-1 is what causes your bones and other tissues to grow. Too much GH leads to too much IGF-1, which can cause acromegaly signs, symptoms and complications.

 

In adults, a tumor is the most common cause of too much GH production:

 

Pituitary tumors. Most acromegaly cases are caused by a noncancerous (benign) tumor (adenoma) of the pituitary gland. The tumor produces excessive amounts of growth hormone, causing many of the signs and symptoms of acromegaly. More accurately the tumor actually produces the excess GH, places pressure on the pituitary gland causing the hormone release.  Some of the symptoms of acromegaly, such as headaches and impaired vision, are due to the tumor pressing on nearby brain tissues.

Nonpituitary tumors. In a few people with acromegaly, tumors in other parts of the body, such as the lungs or pancreas, cause the disorder. Sometimes, these tumors secrete GH. In other cases, the tumors produce a hormone called growth hormone-releasing hormone (GH-RH), which signals the pituitary gland to make more GH.

Complications

If left untreated, acromegaly can lead to major health problems. Complications may include:

 

High blood pressure (hypertension)

High cholesterol

Heart problems, particularly enlargement of the heart (cardiomyopathy)

Osteoarthritis

Type 2 diabetes

Enlargement of the thyroid gland (goiter)

Precancerous growths (polyps) on the lining of your colon

Sleep apnea, a condition in which breathing repeatedly stops and starts during sleep

Carpal tunnel syndrome

Increased risk of cancerous tumors

Spinal cord compression or fractures

Vision changes or vision loss

Early treatment of acromegaly can prevent these complications from developing or becoming worse. Untreated, acromegaly and its complications can lead to premature death.

Many people associate this disease with the life of Andre Rene Roussimoff, AKA, Andre the Giant.  He was a professional wrestler from France and did not know he had the disease.  He simply knew he was a big man and getting bigger.  While wrestling in Japan a physician in the audience recognized all of the signs and symptoms of acromegaly.  He sought an audience with Andre the Giant and shared with him the treatment options which were rather primitive at that time.  Andre the Giant refused treatment for he feared it would end his wrestling career.  By all accounts he lived a complicated and tortured life and died at age 46.  He was 7 foot 4 inches and 520 pounds.

 

Jan Ricks Jennings, MHA, LFACHE

Senior Consultant

Senior Management Services, LLC

 

Jan.Jennings.EagleTalons.net

JanJenningsBlog.Blogspot.com

 

724.733.0509 Office

412.913.0636 Cell

 

November 23, 2021                  

                                                                                   

 

Skin Cancer

 



Skin cancer develops primarily on areas of sun-exposed skin, including the scalp, face, lips, ears, neck, chest, arms, and hands, and on the legs in women. But it can also form on areas that rarely see the light of day — your palms, beneath your fingernails or toenails, and your genital area.

 

Skin cancer affects people of all skin tones, including those with darker complexions. When melanoma occurs in people with dark skin tones, it's more likely to occur in areas not normally exposed to the sun, such as the palms of the hands and soles of the feet.

 

Basal cell carcinoma signs and symptoms

Basal cell carcinoma usually occurs in sun-exposed areas of your body, such as your neck or face.

 

Basal cell carcinoma may appear as:

A pearly or waxy bump

A flat, flesh-colored or brown scar-like lesion

A bleeding or scabbing sore that heals and returns

Squamous cell carcinoma signs and symptoms

 

Most often, squamous cell carcinoma occurs on sun-exposed areas of your body, such as your face, ears and hands. People with darker skin are more likely to develop squamous cell carcinoma on areas that aren't often exposed to the sun.

 

Squamous cell carcinoma may appear as:

 

A firm, red nodule

A flat lesion with a scaly, crusted surface

 

Melanoma signs and symptoms

Melanoma can develop anywhere on your body, in otherwise normal skin or in an existing mole that becomes cancerous. Melanoma most often appears on the face or the trunk of affected men. In women, this type of cancer most often develops on the lower legs. In both men and women, melanoma can occur on skin that hasn't been exposed to the sun.

 

Melanoma can affect people of any skin tone. In people with darker skin tones, melanoma tends to occur on the palms or soles, or under the fingernails or toenails.

 

Melanoma signs include:

 

A large brownish spot with darker speckles

A mole that changes in color, size or feel or that bleeds

A small lesion with an irregular border and portions that appear red, pink, white, blue or blue-black

A painful lesion that itches or burns

Dark lesions on your palms, soles, fingertips or toes, or on mucous membranes lining your mouth, nose, vagina or anus

 

Signs and symptoms of less common skin cancers

Other, less common types of skin cancer include:

 

Kaposi sarcoma. This rare form of skin cancer develops in the skin's blood vessels and causes red or purple patches on the skin or mucous membranes.

 

Kaposi sarcoma mainly occurs in people with weakened immune systems, such as people with AIDS, and in people taking medications that suppress their natural immunity, such as people who've undergone organ transplants.

 

Other people with an increased risk of Kaposi sarcoma include young men living in Africa or older men of Italian or Eastern European Jewish heritage.

 

Merkel cell carcinoma. Merkel cell carcinoma causes firm, shiny nodules that occur on or just beneath the skin and in hair follicles. Merkel cell carcinoma is most often found on the head, neck and trunk.

Sebaceous gland carcinoma. This uncommon and aggressive cancer originates in the oil glands in the skin. Sebaceous gland carcinomas — which usually appear as hard, painless nodules — can develop anywhere, but most occur on the eyelid, where they're frequently mistaken for other eyelid problems.

When to see a doctor

Make an appointment with your doctor if you notice any changes to your skin that worry you. Not all skin changes are caused by skin cancer. Your doctor will investigate your skin changes to determine a cause.

Causes


Skin cancer occurs when errors (mutations) occur in the DNA of skin cells. The mutations cause the cells to grow out of control and form a mass of cancer cells.

 

Cells involved in skin cancer

Skin cancer begins in your skin's top layer — the epidermis. The epidermis is a thin layer that provides a protective cover of skin cells that your body continually sheds. The epidermis contains three main types of cells:

 

Squamous cells lie just below the outer surface and function as the skin's inner lining.

Basal cells, which produce new skin cells, sit beneath the squamous cells.

Melanocytes — which produce melanin, the pigment that gives skin its normal color — are located in the lower part of your epidermis. Melanocytes produce more melanin when you're in the sun to help protect the deeper layers of your skin.

 

 

Ultraviolet light and other potential causes

Much of the damage to DNA in skin cells results from ultraviolet (UV) radiation found in sunlight and in the lights used in tanning beds. But sun exposure doesn't explain skin cancers that develop on skin not ordinarily exposed to sunlight. This indicates that other factors may contribute to your risk of skin cancer, such as being exposed to toxic substances or having a condition that weakens your immune system.

 

Risk factors

Factors that may increase your risk of skin cancer include:

 

Fair skin. Anyone, regardless of skin color, can get skin cancer. However, having less pigment (melanin) in your skin provides less protection from damaging UV radiation. If you have blond or red hair and light-colored eyes, and you freckle or sunburn easily, you're much more likely to develop skin cancer than is a person with darker skin.

Sun exposure accumulated over time also may cause skin cancer.

A history of sunburns. Having had one or more blistering sunburns as a child or teenager increases your risk of developing skin cancer as an adult. Sunburns in adulthood also are a risk factor.

Excessive sun exposure. Anyone who spends considerable time in the sun may develop skin cancer, especially if the skin isn't protected by sunscreen or clothing. Tanning, including exposure to tanning lamps and beds, also puts you at risk. A tan is your skin's injury response to excessive UV radiation.

Sunny or high-altitude climates. People who live in sunny, warm climates are exposed to more sunlight than are people who live in colder climates. Living at higher elevations, where the sunlight is strongest, also exposes you to more radiation.

Moles. People who have many moles or abnormal moles called dysplastic nevi are at increased risk of skin cancer. These abnormal moles — which look irregular and are generally larger than normal moles — are more likely than others to become cancerous. If you have a history of abnormal moles, watch them regularly for changes.

Precancerous skin lesions. Having skin lesions known as actinic keratoses can increase your risk of developing skin cancer. These precancerous skin growths typically appear as rough, scaly patches that range in color from brown to dark pink. They're most common on the face, head and hands of fair-skinned people whose skin has been sun damaged.

A family history of skin cancer. If one of your parents or a sibling has had skin cancer, you may have an increased risk of the disease.

A personal history of skin cancer. If you developed skin cancer once, you're at risk of developing it again.

A weakened immune system. People with weakened immune systems have a greater risk of developing skin cancer. This includes people living with HIV/AIDS and those taking immunosuppressant drugs after an organ transplant.

Exposure to radiation. People who received radiation treatment for skin conditions such as eczema and acne may have an increased risk of skin cancer, particularly basal cell carcinoma.

Exposure to certain substances. Exposure to certain substances, such as arsenic, may increase your risk of skin cancer.

Prevention

Most skin cancers are preventable. To protect yourself, follow these skin cancer prevention tips:

 

Avoid the sun during the middle of the day. For many people in North America, the sun's rays are strongest between about 10 a.m. and 4 p.m. Schedule outdoor activities for other times of the day, even in winter or when the sky is cloudy.

 

You absorb UV radiation year-round, and clouds offer little protection from damaging rays. Avoiding the sun at its strongest helps you avoid the sunburns and suntans that cause skin damage and increase your risk of developing skin cancer

 

Wear sunscreen year-round. Sunscreens don't filter out all harmful UV radiation, especially the radiation that can lead to melanoma. But they play a major role in an overall sun protection program.

 

Use a broad-spectrum sunscreen with an SPF of at least thirty, even on cloudy days. Apply sunscreen generously and reapply every two hours — or more often if you're swimming or perspiring. Use a generous amount of sunscreen on all exposed skin, including your lips, the tips of your ears, and the backs of your hands and neck.

 

Wear protective clothing. Sunscreens do not provide complete protection from UV rays. So, cover your skin with dark, tightly woven clothing that covers your arms and legs, and a broad-brimmed hat, which provides more protection than a baseball cap or visor does.

 

Some companies also sell photoprotective clothing. A dermatologist can recommend an appropriate brand.

 

Do not forget sunglasses. Look for those that block both types of UV radiation — UVA and UVB rays.

 

Lights used in tanning beds emit UV rays and can increase your risk of skin cancer.

Be aware of sun-sensitizing medications. Some common prescription and over-the-counter drugs, including antibiotics, can make your skin more sensitive to sunlight.

 

Ask your doctor or pharmacist about the side effects of any medications you take. If they increase your sensitivity to sunlight, take extra precautions to stay out of the sun in order to protect your skin.

 

Check your skin regularly and report changes to your doctor. Examine your skin often for new skin growths or changes in existing moles, freckles, bumps, and birthmarks.

 

With the help of mirrors, check your face, neck, ears, and scalp. Examine your chest and trunk, and the tops and undersides of your arms and hands. Examine both the front and back of your legs, and your feet, including the soles and the spaces between your toes. Also check your genital area and between your buttocks.

 

Jan Ricks Jennings

Senior Consultant

Senior Management Resources, LLC

 

Jan.Jennings@EagleTalons.net

JanJenningsBlog.Blogspot.com

 

724.733.0509 Office

412.913.0636 Cell

November 22, 2021